Observe Closely (2)istradefylline will increase the level or influence of pazopanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pazopanib will improve the amount or influence of ruxolitinib topical by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unknown.rifapentine will lower the level or effect of pazopani

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